Mechanisms of Physical and Emotional Stress - Advances in Experimental Medicine and Biology - George P. Chrousos - Livros - Springer-Verlag New York Inc. - 9781489920669 - 18 de julho de 2013
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George P. Chrousos
Mechanisms of Physical and Emotional Stress - Advances in Experimental Medicine and Biology Softcover reprint of the original 1st ed. 1988 edition

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It has been over 50 years since Hans Selye formulated his concept of stress. This came after the isolation of epinephrine and norepinephrine and after the sympathetic system was associated with Walter Cannon's "fight or flight" response. The intervening years have witnessed a number of dis­ coveries that have furthered our understanding of the mechanisms of the stress response. The isolation, identification and manufacture of gluco­ corticoids, the identification and synthesis of ACTH and vasopressin, and the demonstration of hypothalamic regulation of ACTH secretion were pivotal discoveries. The recent identification and synthesis of CRR by Willie Vale and his colleagues gave new impetus to stress research. Several new concepts of stress have developed as a result of advances in bench research. These include the concept of an integrated "stress sys­ tem", the realization that there are bi-directional effects between stress and the immune system, the suggestion that a number of common psychiatric disorders represent dysregulation of systems responding to stress, and the epidemiologic association of stress with the major scourges of humanity.

530 pages, 40 black & white illustrations, biography

Mídia Livros     Paperback Book   (Livro de capa flexível e brochura)
Lançado 18 de julho de 2013
ISBN13 9781489920669
Editoras Springer-Verlag New York Inc.
Páginas 530
Dimensões 155 × 235 × 28 mm   ·   752 g
Idioma Inglês  

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