Heat Shock Proteins in Cancer - Heat Shock Proteins - Stuart K Calderwood - Livros - Springer-Verlag New York Inc. - 9781402064005 - 21 de setembro de 2007
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Stuart K Calderwood
Heat Shock Proteins in Cancer - Heat Shock Proteins 2007 edition

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Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy.

Marc Notes: Includes bibliographical references and index. Table of Contents: The Hsp90 Chaperone Machinery Acts at Protein Folding Clefts to Regulate Both Signaling Protein Function and Protein Quality Control.- Implications of Heat Shock Proteins in Carcinogenesis and Cancer Progression.- HSF1: An Emerging Factor In Cancer.- Anti-apoptotic, Tumorigenic and Metastatic Potential of Hsp27 (HspB1) and ?B-crystallin (HspB5): Emerging Targets for the Development of New Anti-Cancer Therapeutic Strategies.- Heat Shock Protein-27 (Hsp-27) in Breast Cancers: Regulation of Expression and Function.- Role of Heat Shock Protein Hsp25/27 in the Metastatic Spread of Cancer Cells.- Heat shock chaperone mortalin and carcinogenesis.- Role of Molecular Chaperones in Cell Senescence.- Involvement of Heat Shock Proteins in Protection of Tumor Cells from Genotoxic Stresses.- Hsp70 in Tumors: Friend or Foe?.- Hsp70 and Hsp27 as pharmacological targets in apoptosis modulation for cancer therapy.- Heat Shock Protein 90: The Cancer Chaperone.- Targeting Hsp90 Function to Treat Cancer: Much More to Be Learned.- Small-molecule Hsp90 Inhibitors: Applications in Cancer and Neurodegenerative diseases.- Drugging the Hsp90 molecular chaperone machine for cancer treatment.- Cdc37 and protein kinase folding.- The Elevated Levels of Heat Shock Proteins In Cancer: A Suitable Case For Treatment?.- Hsp70-Based Anticancer Vaccines: Chaperoning The Immune Response.- Piloting of exogenous antigen into cross-presentation pathway by heat shock proteins.

Mídia Livros     Hardcover Book   (Livro com lombada e capa dura)
Lançado 21 de setembro de 2007
ISBN13 9781402064005
Editoras Springer-Verlag New York Inc.
Páginas 400
Dimensões 155 × 235 × 23 mm   ·   825 g
Idioma Inglês  
Editor Calderwood, Stuart K.
Editor Ciocca, Daniel R.
Editor Sherman, Michael Y.

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